PhD Position (m/f/d) – Krombach Fellow (Bioinformatiker/in)

PhD Position (m/f/d) – Krombach FellowFull- or Part-time | Fixed-term (36 months) | Institute of Human GeneticsJoin an internationally recognized research team investigating the genetic foundations of sleep disorders through large-scale genomic analyses and machine learning. As the Krombach Fellow, you will contribute to a global multi-ancestry research consortium and help advance precision medicine approaches for restless legs syndrome.Your responsibilities:- Design and conduct genome-wide association studies (GWAS) and large-scale multi-ancestry meta-analyses using international biobank and research datasets.- Apply advanced statistical genetics methods to identify and prioritize disease-associated variants, genes, and biological pathways. - Develop and benchmark machine-learning models for genetic risk prediction across diverse populations. - Integrate genomic, clinical, and functional genomics data to improve the understanding of sleep disorders and their biological mechanisms. - Build reproducible, version-controlled analysis pipelines on high-performance computing and cloud platforms. - Present research findings within an international consortium and contribute to high-impact scientific publications.Your profile:- Master’s degree (or equivalent) in bioinformatics, statistics, mathematics, computer science, machine learning, human genetics, epidemiology, or a closely related quantitative discipline. - Strong programming skills in Python and/or R to analyze and interpret large-scale genomic and health-related datasets. - Solid understanding of applied statistics, including regression models, multiple testing, and causal inference, enabling robust analysis of complex biological data. - Experience working with large datasets and high-performance computing environments to manage computationally intensive genomic analyses. - Interest in human disease biology and motivation to translate genetic discoveries into clinically relevant insights through collaboration with clinicians and experimental researchers. - Excellent written and spoken English skills to communicate findings effectively within an international research consortium and at scientific conferences.We offer you:- A temporary position with the possibility of extension- EGYM well pass, corporate benefits and discounts (e.g.

Käfer), cafeteria, sports and cultural offers, company bike - Working in the heart of Munich at Max-Weber-Platz with very good accessibility by public transport such as the subway, S-Bahn or tram- Company pension plan through the Federal and State Pension Institute (VBL)- Self-realization through a varied and technically demanding job with interdisciplinary cooperation between various departments of the TUM KlinikumWe look forward to your application!For further information, please contact Prof.

Dr. Juliane Winkelmann, Tel. 089 / 4140 - 1445Institute of Human GeneticsTUM KlinikumRechts der IsarIsmaninger Straße 2281675 MünchenIf the candidates’ suitability for the position in question is equal, severely disabled applicants shall be given preference.Interview-related costs can, unfortunately, not be reimbursed.