Postdoc (f/m/x) - Neuroscience, Epigenetics and Metabolic Aging

Postdoc (f/m/x) – Neuroscience, Epigenetics and Metabolic Aging

103020

Full time

39 hrs./week

Neuherberg near Munich

At Helmholtz Munich, we develop groundbreaking solutions for a healthier

society in a rapidly changing world. We believe that diverse perspectives drive

innovation. Through strong partnerships, we accelerate the transfer of new

ideas from the lab to real-life applications, improving lives.

The Institute for Diabetes and Cancer (IDC)at Helmholtz Munich aims to

elucidate the molecular mechanisms linking metabolic dysfunction, diabetes, and

tumorigenesis. The research groupMetabolic Programming across Generations

investigates how environmental and nutritional factors during early life and

across generations affect metabolic health and disease susceptibility later in

life.

We are seeking a highly motivated Postdoctoral Researcher (f/m/x)to join our

interdisciplinary and international research team as part of a project funded

through the DZD NEXT Young Talent Program of the German Center for Diabetes

Research (DZD).

The project aims to understand whether maternal metabolic stress during early

development accelerates aging processes in the brain, particularly in brain

regions that control metabolism. Using a cross-species approach, we will

investigate the molecular and epigenetic mechanisms linking early-life

metabolic conditions to brain aging and metabolic health later in life.

The position is available from January 2027 and is funded for two years.

Your tasks

- Conduct experimental research to investigate the molecular and epigenetic

mechanisms linking early-life metabolic stress to hypothalamic aging and

metabolic health

- Perform studies in murine models, including collection, processing,

sectioning of brain tissue and anatomical analysis of hypothalamic regions

- Apply molecular, histological, and epigenetic approaches to characterize

aging-associated changes in the hypothalamus

- Analyze and integrate high-dimensional sequencing datasets, including

RNA-seq, single-cell/single-nucleus sequencing, ATAC-seq and/or ChIP-seq data

- Develop research questions independently and contribute intellectually to

the further development of the project

- Work closely with members of our research group and collaborators within

Helmholtz Munich and the DZD network

- Present and communicate research findings through publications, seminars,

and national and international scientific conferences

Your profile

- PhD in neuroscience, molecular biology, physiology, biochemistry,

bioinformatics, or a related field, with a strong interest in metabolic aging

and/or neurobiology

- Strong research experience in molecular biology, neuroscience, metabolism,

or a related field, combined with the ability to independently develop and

pursue scientific questions

- Experience with high-throughput sequencing data analysis, such as RNA-seq,

single-cell/single-nucleus RNA-seq, ATAC-seq, or ChIP-seq

- Strong scientific curiosity, problem-solving skills, and a proactive,

independent working style

- Excellent communication skills and enthusiasm for interdisciplinary

collaboration in an international research environment

- Excellent written and spoken English

Desirable qualifications

- Experience with murine models, brain tissue processing, mouse neuroanatomy,

or hypothalamic/neuroendocrine research

- Experience with immunohistochemistry, RNAscope/in situ hybridization,

metabolic phenotyping, or spatial molecular approaches

- Experience with single-cell/single-nucleus genomics and/or epigenomic data

analysis

If you fulfill all the requirements, you may be eligible for a salary grade

of up to E 13. Social benefits are based on the Collective Wage Agreement for

Public-Sector Employees (TVöD). The position has an (initial) fixed term of two

years but may be extended under certain circumstances.

Managing Director Mike Frieser:

„We believe that diversity is the key to groundbreaking research and

innovative solutions. Our flexible working models and remote options create a

supportive environment for balancing work and family life. For us, contributing

to a healthier society in such an inspiring workplace is truly meaningful.“

Get to know us

Benefits

- Scientific Resources

State-of-the-art infrastructure and Core Facilities

- International Staff Service

Support with the relocation and integration process in Germany

- Career Development

Postdoc program, scientific training & career center with tailored offers

- Recreation

30 days annual leave, flexi days, plus public holidays

- Health Promotion

Sports, company doctor, mental health initiatives

- Family Support

On-site kindergarten, holiday care, care for the elderly

Interested in applying?

If you have any questions, feel free to contact Merly Carlotta Bonetta-Vogt,

+4989318748674, who will be happy to help.